The Puzzle of Vitiligo, Oxidative Stress and Narrow Band Ultraviolet-B

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The Puzzle of Vitiligo, Oxidative Stress and Narrow Band Ultraviolet-B

Obviously, vitiligo is a multifactorial disease, and at this stage, we all accept that the autoimmune theory, the adhesion defect theory and the biochemical theory based on oxidative stress are the mainstays of our current knowledge about the aetiology of the disease. The presence of an imbalance in the anti-oxidant system in vitiligo melanocytes was assessed early, providing support for a free...

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Evaluation of Efficacy and Safety of Combination of Narrow Band Ultraviolet B and Topical Calcipotriol Versus Narrow Band UVB alone in the Treatment of Vitiligo

Background: Narrow band Ultraviolet B (NBUVB) has been used successfully for the treatment of vitiligo. Recently, topical calcipotriol has also been used as immunotherapy or as a part of combination therapies. The aim of this study was to compare the clinical efficacy and safety of NBUVB and NBUVB plus topical calcipotriol in the treatment of generalized vitiligo.Methods: NBUVB phototherapy was...

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hmb-۴۵ study before and after narrow-band (۳۱۱ nm) ultraviolet b treatment in vitiligo

conclusions the hmb-45 stain strength significantly changed after treatment in perilesional skin. results twenty-nine patients completed the study. the wilcoxon test showed a meaningful relation between hmb-45 staining before and after nb-uvb treatment in perilesional skin. we did not find a meaningful relation between hmb-45 staining before and after treatment regarding the mean age, gender, m...

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Narrow band Ultraviolet B 311 nm in the treatment of vitiligo: two right-left comparison studies.

AIM Evaluation of narrow band ultraviolet B (NB UVB 311 nm) in the treatment of vitiligo by two independent studies. The first study compared NB UVB with a well-established therapeutic modality, psoralen ultraviolet A (PUVA), and the second study was conducted to find out whether psoralen might add to its efficacy. METHODS In the first study, 15 patients were exposed on the left half of their...

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Narrow Band-Ultraviolet B Versus Clobetasol Propionate Foam in the Treatment of Vitiligo: A Retrospective Study

INTRODUCTION Several therapeutic options are available for the treatment of vitiligo; among these phototherapy and topical steroids are the most widely documented. A topical formulation of 0.05% clobetasol propionate foam (CPF) has been introduced in the market, but no data are available about the efficacy and tolerability of this new formulation in the treatment of vitiligo. The aim of this st...

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ژورنال

عنوان ژورنال: Dermatology Case Reports

سال: 2016

ISSN: 2684-124X

DOI: 10.35248/2684-124x.16.1.113